Triterpenoids from the roots of Sanguisorba tenuifolia var. Alba.
نویسندگان
چکیده
The ethyl acetate soluble fraction from the roots of Sanguisorba tenuifolia was found to have a hypoglucemic effect in alloxan-induced diabetic rats. Two new triterpenoids, identified as 2-oxo-3β,19α-dihydroxyolean-12-en-28-oic acid β-D-gluco-pyranosyl ester (1) and 2α,19α-dihydroxy-3-oxo-12-ursen-28-oic acid β-D-glucopyranosyl ester (4) were isolated from this fraction, along with thirteen known triterpenoids. Their structures were elucidated by chemical and spectroscopic methods. All these compounds demonstrated inhibitory activities against α-glucosidase with IC₅₀ values in the 0.62-3.62 mM range.
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ورودعنوان ژورنال:
- Molecules
دوره 16 6 شماره
صفحات -
تاریخ انتشار 2011